Glycosyl compounds
Medchemexpress LLC Gala | 107658-43-5 | 99.04% | 3032.36 | 10 MG
GALA is a pH-responsive amphipathic peptide composed of 30 amino acids, functioning as a lung endothelium-targeting ligand. It transitions from a random coil to an α-helix in an acidic environment (pH 5.0), leading to endosomal membrane destabilization and fusion. GALA-modified liposomes cross lung endothelial cells via clathrin-dependent endocytosis and transcytosis, accumulating specifically in the lungs after intravenous injection.
- Enhances cytosolic release of cargos from exosomes, plasmids, and liposomes
- Improves gene transfection efficiency and drives gene knockdown of functional macromolecules (e.g., siRNA) in alveolar epithelial cells
- Vital tool for studying lung cancer metastasis and lung-targeted drug delivery systems
- No significant cytotoxicity at effective concentrations
Medchemexpress LLC Isrib (trans-isomer) | 1597403-47-8 | 99.49% | 451.34 | 50 MG
ISRIB (trans-isomer) is a potent inhibitor of PERK with an IC50 of 5 nM. It effectively reverses the effects of eIF2α phosphorylation and reduces the viability of cells subjected to PERK-activation by chronic endoplasmic reticulum stress. This trans-isomer is 100-fold more potent than cis-ISRIB, demonstrating stereospecific interaction with its cellular target.
- Potently reverses eIF2α phosphorylation (IC50=5 nM)
- Blocks eIF2α phosphorylation-induced stress granule (SG) formation
- Increases long-term memory in rodents
- Readily crosses the blood-brain barrier
Medchemexpress LLC Quercetin-3-O-D-glucosyl]-(1-2)-L-rhamnoside | 143016-74-4 | 10 MG
Quercetin-3-O-D-glucosyl]-(1-2)-L-rhamnoside is a flavonoid glycoside with antioxidant activity and free radical scavenging activity. It effectively scavenges free radicals, including ABTS+, making it valuable for research into antioxidant-related diseases such as cardiovascular and neurodegenerative conditions.
- A flavonoid glycoside with antioxidant properties
- Scavenges free radicals like ABTS+
- Useful in the study of cardiovascular and neurodegenerative diseases
- Classified as a flavonoid, flavonol, phenol, and polyphenol
- Naturally sourced from plants such as Ginkgo biloba
Medchemexpress LLC Loureirin D | 119425-91-1 | 1 MG
Loureirin D is a dihydrochalcone identified in dragon's blood. This product is for research use only and not for human use.
- Molecular weight: 288.30
- Formula: C16H16O5
- Appearance: Solid
- Color: White to pink
- Structure classification: Phenols, polyphenols
- Initial source: Plants other families
- Purity: 99.30%
- Store at 4°C, protected from light
- Store in solvent at -80°C for 6 months or -20°C for 1 month (protected from light)
Medchemexpress LLC Sucralose | 56038-13-2 | 397.63 | 50 MG
Sucralose (Standard) is the analytical standard of Sucralose, intended for research and analytical applications. It is a non-nutritive artificial sweetener and sugar substitute (E955; Trichlorosucrose). This compound can activate a conserved neural fasting response, leading to an appetite-stimulating effect in rodents. It is commonly used in qualitative, quantitative, and methodological research experiments in HPLC, GC, and MS.
- Analytical standard for Sucralose.
- Intended for research and analytical applications.
- Non-nutritive artificial sweetener and sugar substitute.
- Activates a conserved neural fasting response, stimulating appetite in rodents.
- Used in qualitative, quantitative, and methodological research experiments (HPLC, GC, MS).
- Purity: 99.72%.
Medchemexpress LLC 4-Nitrophenyl-N-acetyl-β-D-glucosaminide | 3459-18-5 | MFCD00063696 | 100.0% | 342.30 | 250 MG
4-Nitrophenyl-N-acetyl-β-D-glucosaminide is an artificial substrate of N-acetyl-beta-D-hexosaminidase (NAGase), used in rapid and accurate rate assays for N-acetyl-beta-D-hexosaminidase. It is highly soluble and stable, and can be used for the study of renal tubular injury.
- Artificial substrate of N-acetyl-beta-D-hexosaminidase (NAGase)
- Used in rapid and accurate rate assays for N-acetyl-beta-D-hexosaminidase
- Highly soluble and stable
- Can be used for the study of renal tubular injury
Medchemexpress LLC Terrestrosin D | 179464-23-4 | 10MM/1ML
Terrestrosin D is an orally active apoptosis inducer. It induces cell cycle arrest at the G1 and S phases, reduces mitochondrial membrane potential, and inhibits the growth of cancer cells and endothelial cells. It is studied in castration-resistant prostate cancer and pulmonary fibrosis.
- Orally active apoptosis inducer
- Induces cell cycle arrest at G1 and S phases
- Reduces mitochondrial membrane potential
- Inhibits the growth of cancer cells and endothelial cells
- Studied in castration-resistant prostate cancer and pulmonary fibrosis
Medchemexpress LLC Ophiopogonin D | 945619-74-9 | 855.02 | 10 MM * 1 ML
Ophiopogonin D is a naturally occurring C29 steroidal glycoside isolated from *Ophiopogon japonicus*. It acts as a CYP2J3 inducer and shows protective effects against inflammatory, metabolic, and cardiovascular diseases.
- Inhibits Ang II induced NF-κB nuclear translocation.
- Increases expression of CYP2J2/EETs and PPARα in HUVECs.
- Inhibits osteoclastic differentiation in RAW264.7 cells.
- Protects against H2O2-induced endothelial injury as an antioxidant.
- Blocks ERK signaling cascades.
- Alleviates high-fat diet-induced metabolic syndrome.
Medchemexpress LLC D-(+)-Trehalose dihydrate | 6138-23-4 | 378.33 | 25 MG
D-(+)-Trehalose dihydrate (Standard) is the analytical standard of D-(+)-Trehalose dihydrate, isolated from Saccharyomyces cerevisiae. It serves as a reference standard for research and analytical applications, and can also be used as a food ingredient and pharmaceutical excipient.
- Intended for research and analytical applications.
- Isolated from Saccharomyces cerevisiae.
- Can be used as a food ingredient.
- Can be used as a pharmaceutical excipient.
- Utilized in qualitative, quantitative, and methodological research experiments.
- Suitable for techniques such as HPLC, GC, and MS.
Medchemexpress LLC Pulsatilla saponin D | 68027-15-6 | 913.10 | 1 ML
Pulsatilla saponin D (SB365), also known as Hederacolchiside A, is a natural product isolated from the root of Pulsatilla chinensis. It is an anti-tumor agent.
- Shows apoptotic effect.
- Strongly inhibits c-Met expression in gastric cancer cells.
- Suppresses the growth and proliferation of 5 human pancreatic cancer cell lines.
- Exhibits anti-angiogenic activity.
- Shows anti-tumor activity in NSCLC cancer cells.
- Demonstrates anti-tumor activity in a Lewis lung carcinoma model.
Medchemexpress LLC Sucrose octasulfate sodium | 74135-10-7 | 98.0% | 1158.66 | 100 MG
Sucrose octasulfate sodium is a derivative of sulfated oligosaccharides that acts as a matrix metalloproteinase (MMP) inhibitor. It stimulates the release of somatostatin-like immunoreactivity (SLI) from the stomach by directly affecting D cells in the gastric mucosa, contributing to its ulcer-healing effect. It can also be used as a pharmaceutical excipient and has shown to improve wound closure in diabetic foot ulcers and venous leg ulcers.
- Stimulates somatostatin-like immunoreactivity (SLI) release
- Exerts ulcer-healing effects
- Can be used as a pharmaceutical excipient
- Improves wound closure in diabetic foot ulcers and venous leg ulcers
- Suitable for chronic wound healing studies
Medchemexpress LLC 4-nitrophenyl-n-acetyl-α-d-galactosaminide | 23646-68-6 | MFCD00065476 | 99.9% | 342.30 g·mol⁻1 | C14H18N2O8 | 10 MG
4-Nitrophenyl-N-acetyl-α-D-galactosaminide (pNP-GalNAc) is a chromogenic substrate for N-acetyl-D-galactosaminase used in enzyme assays and kinetic studies. Enzymatic cleavage liberates 4-nitrophenol, producing a measurable absorbance change for quantitative activity determination.
- Chromogenic substrate for N-acetyl-D-galactosaminase.
- Enables quantitative measurement of enzyme activity by absorbance.
- High reported purity (≈99.9%).
- Solid form, white to off-white, suitable for standard assay preparation.
- Store at 4°C and protect from light for optimal stability.